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You might have nausea, vomiting, diarrhea, bloating, etc

Scripts of the 0.25mg starter dose are -37% w/w and it is known Novo restricts this supply to constrain new patient starts, perhaps implying current supply bottlenecks, just at the time competitor Lilly has removed the shortages of Mounjaro/Zepbound. Next Wave of GLP-1s So much attention in the GLP-1 space is on the Lilly-Novo duopoly, which is expected to retain around 70% of a potential $200 billion total market, according to a report last month from PitchBook and Morningstar

Anorectal dose-effect relations for late gastrointestinal toxicity following external beam radiotherapy for prostate cancer in the FLAME trial

The key difference is that tirzepatide generally produces more weight loss, more quickly, which means the adjustment period may be more pronounced but the long-term sleep benefits (from greater weight loss and sleep apnea improvement) may also be greater

This early appetite shift is not psychologicalit reflects real changes in the hormonal signals that drive eating behavior