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Clinicians presently recommend aiming for the lowest effective dose and administering the peptide at about 600mg/weekly, split into six injections throughout the week

But the FDA flagged a serious adverse event, including a death, associated with an IV ipamorelin infusion (although it wasnt clear whether the peptide directly caused the participant's death)

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Studies also show that giving exogenous melatonin to animals also increases survival time in a similar manner to calorie restriction.[ref] Not all studies show this, so it may be species-specific