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doi: 10.1016/j.isci.2024.110864 26 GuoLZhaoYBaiXWangXTuohetiKCaoYet al

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(vi) signal transduction from the environment to cellular transcription machinery ( GSH AS MAIN REGULATOR OF CELLULAR REDOX STATUS AND REDOX SIGNAL TRANSDUCTION The glutathione redox couple GSH/GSSG has a great importance in the cells and together with other redox-active couples, including NADPH/NADP + , Trx-SH/Trx-SS regulates and maintains the appropriate cellular redox status

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