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they must be packaged into very-low-density lipoprotein (VLDL) particles, which require phosphatidylcholine as the structural membrane component
Patients with Lebers disease, a rare hereditary optic neuropathy, should avoid methylcobalamin supplementation as it may precipitate or worsen optic atrophy in affected individuals
Many set their own thresholds, and those thresholds can be significantly more restrictive than what the FDA approves
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