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With this in mind, we adapted an alternative approach to hydrophobize the surface of GSH-AuNCs that relies on the electrostatic interaction between hydrophobic cationic phase transfer agent (namely dodecylamine, DDA) and the negatively charged GSH-AuNCs

Early studies discovered a reduced incretin effect in individuals with type 2 diabetes following oral glucose intake 16,17,18

Unlike other hormetic stressors, such as radiation or chemical exposure, which may carry inherent risks and require careful management, dietary hormesis involves the consumption of natural foods rich in bioactive compounds, such as fruits, vegetables, and whole grains 2,3,4

For instance, administration must occur in a fasted state (at least 2-3 hours post-meal) because elevated insulin and blood glucose can significantly blunt the pituitarys response to secretagogues

In individuals with T2D, poor adherence and persistence represent barriers to achieving optimal care [37]