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Protective effects of MDG-1, a polysaccharide from Ophiopogon japonicus on diabetic nephropathy in diabetic KKAy mice

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As mentioned previously, NRF2 regulates the expression of ATF4, which controls the expression of the glutamine transporter SLC1A5 [73], and asparagine synthetase (ASNS), which generates both asparagine and glutamate from aspartate and glutamine