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A MASLD substudy within the phase 2 obesity trial of retatrutide provided compelling evidence of hepatic benefits
It was interesting that 13 samples showed a direct correlation for GLP-1R expression between the primary site and its metastatic counterpart, while the remaining two samples with negative GLP-1R expression in the primary site showed positive GLP-1R expression in the metastatic site, suggesting that cells expressing GLP-1R may have an increased metastatic ability
CampbellBCVMitchellPJKleinigTJDeweyHMChurilovLYassiNet al
10.1038/s42255-018-0017-4 27 CerfM
According to NICE guidance (NG28), GLP-1 receptor agonists are recommended as treatment options for type 2 diabetes when certain criteria are met
