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doi: 10.2139/ssrn.4653984 132 SanzABSanchez-NinoMDRamosAMOrtizA

2b), suggesting these immunometabolic changes are independent of CAR expression

In Capsoni et al.'s study, intranasal administration of human nerve growth factor painless (hNGFp) was performed in Ts65Dn mice at an early stage, before the accumulation of amyloid precursor protein (APP) leading to neurodegeneration

Nat Neurosci 11(4):420422 Winkler EA, Sengillo JD, Sagare AP, Zhao Z, Ma Q, Zuniga E et al (2014) Bloodspinal cord barrier disruption contributes to early motor-neuron degeneration in ALS-model mice