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10.1016/j.abb.2008.06.004 Arch Biochem Biophys
Neuroinflammation can be caused by different immune components such as activated glia, chemokines, infectious diseases or immune/autoimmune disorders, and each of them has a different impact on each step of adult neurogenesis, either positive or negative depending on various factors, such as chronicity or severity of the inflammation ( Here we review studies that have revealed transcriptomic changes occurring in the hippocampus or NSCs of models of neurodegenerative, mental health and neurodevelopmental disorders as well as neuroinflammation models associated with altered neurogenesis, such as spontaneously hypertensive rats, TLX knockout or HIV infected mice, and a Systemic lupus erythematosus mouse model
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