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As laboratories move toward quicker analytical cycles and smaller sample volumes, magnetic beadbased workflows provide an efficient and highly adaptable alternative to traditional purification techniques
The novel ATR inhibitor BAY 1895344 is efficacious as monotherapy and combined with DNA damage-inducing or repair-compromising therapies in preclinical cancer models
This binding makes the toxic compound more water soluble and assists in the bodys efforts in eliminating the toxin (4)
Brain tissues were fixed in 10% formalin (Sigma-Aldrich, HT501128, Massachusetts, USA) for 48 h, dehydrated through a graded ethanol series (Merck, 6417-5, Darmstadt, Germany), cleared in xylene (VWR Chemicals, 133020-7, Mississauga, Canada), and embedded in paraffin wax (Leica Biosystems, 3801320, Illinois, USA)