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AOD 9604/MOTS-c is given as a subcutaneous injection on a provider-determined schedule

Activation of these receptors triggers two complementary processes: it accelerates lipolysis (the breakdown of stored triglycerides into free fatty acids for energy) while simultaneously inhibiting lipogenesis (the conversion of glucose and other substrates into new fat stores)

Le Chatelier, E

Peripherally, pancytopenia is most often observed, but only 12 of the major cell types (erythrocytes, leukocytes, platelets) may be depressed in some cases

In these studies, AOD-9604 administered via intraperitoneal injection produced significant fat mass reduction without changes in food intake or lean body mass