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Loren Pickart, who found that it caused older human liver tissue to produce proteins more characteristic of younger tissue.2 3 This resulted in GHK being originally described, specifically, as a liver cell growth factor

Instead, they recommended methylcobalamin, a form of B12 where a methyl group replaces the cyano group

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Previous studies have reported inconsistent results when comparing oral, sublingual, and intramuscular administration, often limited by small sample sizes or heterogeneous populations (Vidal-Alaball et al., 2006

JAMA 312 , 137144 (2014)