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This study showed that PLC expression was elevated in prostate cancer samples, and targeted silencing of PLC inhibited cell growth and proliferation of LNCaP and PC3 cells, decreased the expression levels of androgen receptor, Hes-1 and Notch, and blocked AR translocation to the nucleus

A review published in PubMed found that berberine induces GLP-1 secretion in the intestine by altering the bacterial profile and promoting short-chain fatty acid production from intestinal L-cells

The GSTF8 gene was also induced by H 2 O 2 through the activation of MPK3/MPK6 kinases (Kovtun et al., 2000) the promoter of which contains an as-1 motif, which is implicated in response to oxidative stress (Garretn et al., 2002)

This kinase is also known as phosphatidylinositol-3-phosphate 5-kinase type III (PIPKIII)

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