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In a retrospective study GLP-1 agonists have been shown to be associated with lower rates of hepatic decompensations compared to other glycemic agents, although more prospective data is needed
JAMA Network Open, 7(5), e2413172
Another nuclear receptor, peroxisome proliferator-activated receptor (PPAR-), modulates gene expression related to inflammation and mediates antimycobacterial responses against M.tb infection by activating the expression of genes associated with autophagy, lysosomal function, and phagosomal maturation through lipid catabolism and upregulation of TFEB transcription[54]
