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Ciardullo S, Cannistraci R, Mazzetti S, Mortara A, Perseghin G
Phase IV clinical trial BLOSSOM proved that both pregabalin and duloxetine are effective medications for treating pain in DPN in more than 86% (173/201) of randomised patients [90]
It incorporates key modifications, including 14E/17R mutations to stabilize an -helical segment via a salt bridge, multiple proline substitutions (25P, 28P, 29P) to reduce -sheet formation, and N-terminal C20 fatty diacid lipidation for reversible albumin binding (Kruse et al
Methods and Protocols in Food Science
Rotate sites to prevent tissue damage
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