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Conversely, a conserved stretch of N-terminal residues from 31 to 35 (residues SRLDQxFG) in HspB1, HspB6, and HspB8 has been identified as a negative regulator of activity (Tedesco et al., 2022)
2011;6(4): e18604
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FIGURE 5 Ebselen has also been tested in combination with other ATs that may improve its efficacy
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