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In summary, FOXO4-DRI exerts its anti-aging effects by inhibiting the binding of FOXO4 to P53, promoting P53 phosphorylation, and facilitating the translocation of p-P53 from the nucleus to the cytoplasm for its functional role
JAMA Psychiatry 2025: 0679
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Lastly, lifestyle factors, such as excessive red meat consumption, sedentary behavior, and smoking, pose additional risks
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