Consistent with these biological roles, cytokine analysis revealed that EGCG-Zn significantly downregulated the pro-inflammatory cytokines IL-6 and TNF- while upregulating the anti-inflammatory cytokine IL-10 (Fig
doi: 10.1001/jamanetworkopen.2020.33457 136 GaritoTRoubenoffRHompeschMMorrowLGomezKRooksDet al
Wei KN, Wang XJ, Zeng ZC, Gu RT, Deng SZ, Jiang J, et al
It helps lighten dark spots, firm the skin, and reduce the appearance of wrinkles
SLC25A32 is the mitochondrial carrier for the tetrahydrofolate (THF) species in mitochondrial one-carbon (1 C) metabolism, as demonstrated by in vitro studies 23 , mouse genetics 24 and cell culture characterization 25,26,27