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It works by: Increasing insulin secretion when glucose is high Reducing glucagon secretion Slowing gastric emptying Reducing appetite and increasing satiety It is FDA-approved for: Type 2 diabetes management Reducing the risk of cardiovascular events in patients with diabetes and known heart disease Although not FDA-approved for weight loss, many clinicians prescribe it off-label

Gradual weight loss Once the medication has reached its maximum concentration and is exerting its full effect, it takes quite a bit of time to lose weight

Nimni, Marcel E., et al

NSL literature pointer PMID 29456846 L-Carnitine laboratory index [PMID: 29456846] National Science Labs indexing note for PMID 29456846: review the PubMed methods, models, and limitations before citing

Gastric bypass leads to the greatest weight loss (about 33%) and shows the greatest success for resolving diabetes