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doi:10.4093/dmj.2025.0242 3
Summary: GLP-1/GIP medications help reduce inflammation in metabolic organsnot autoimmune or pain-related inflammation They DO: lower CRP and related metabolic inflammatory/oxidative stress biomarkers, improve metabolic liver disease activity in steatohepatitis settings, improve cardiometabolic risk markers such as blood pressure improve kidney outcomes in high-risk CKD populations (semaglutide
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Post-reconstitution storage is more restrictive
Prior efforts to treat obesity demonstrate that sustained weight reduction is a Herculean task--thus it may be the case that GLP-1 agents will need to be administered chronically to sustain anti-obesity benefits
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