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Studies have shown that TMAO is an independent risk factor for the occurrence of malignant adverse cardiovascular events, but whether it is harmful or beneficial to patients with cardiovascular diseases with mild or no clinical manifestations remains controversial

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However, glycemic variability showed statistically significant differences between the two groups, with the MMGR being 24% higher in the group with prior cholecystectomy ( p = 0.049, Table 2)

Stentz NC, Koelper N, Barnhart KT, Sammel MD, Senapati S