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Free Radic Res 25(2):149159
The GLP-1 receptor is a class B G protein-coupled receptor (GPCR) found in: Pancreatic beta cells Hypothalamic and brainstem nuclei Gastrointestinal tract Heart, kidney, and elsewhere Upon activation, it triggers multiple intracellular pathways: cAMP/PKA: enhances insulin secretion PI3K/Akt: promotes cell survival and beta cell function MAPK/ERK: involved in cell proliferation, differentiation, and potentially neuroprotective effects These pathways interact in complex ways depending on cell type, receptor density, and ligand properties
Because of the diversity, flexibility and adaptable approach of this style of eating, its easy to begin and to stick with
Disord ., 24 (16), 23582362
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