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Moderate credibility of ICEMAN results shows that L-carnitine supplementation has no difference in changes of AST and ALT levels in younger ones (MD: 0.5, 95%CI: 0.70 to 1.70) but has significant changes (reduced) in adults (MD: 20.3, 95%CI: 28.62 to 12.28) compared to placebo
126 Schoenen, J., Lenaerts, M
Given the strong early trial outcomes of 20-25% average weight loss, many believe Lilly will aim for a fast-track or priority review designation
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