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Using both is generally considered safe, and the combination might theoretically be synergistic for migraine prevention, with CGRP inhibitors blocking the receptor directly while tirzepatide reduces CGRP production upstream
Vila Petroff MG, Egan JM, Wang X, Sollott SJ: Glucagon- like peptide-1 increases cAMP but fails to augment contraction in adult rat cardiac myocytes
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Your healthcare provider can evaluate whether compounded semaglutide is best for your weight loss treatment plan
The oral route has different bioavailability and requires specific dosing instructions, including taking the tablet on an empty stomach with a small amount of water and waiting 30 minutes before eating or drinking anything else
