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While semaglutide targets one hormone receptor (GLP-1), tirzepatide targets two: GLP-1 and GIP
The claim that it has no appetite effect comes from its comparison with GHRP-6 on ACTH and cortisol, a different endpoint
Seminars Cell Dev
The theory is that the bodys signaling pathways reach their limit at low concentrations regardless of body size
As it was previously mentioned the secondary outcome measures observed by the researchers included gastrocnemius muscle mass and foot flexion contractures
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