The greater weight loss seen with retatrutide likely stems from its triple-hormone mechanism
It was sold for over a decade before also being withdrawn due to increased risk of myocardial infarction and stroke: risks that werent justified by the modest effects on body weight
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Funding This work was supported by the National Natural Science Foundation of China (8247143079), The Discipline Construction Project of Hunan University of Chinese Medicine (Z2023JBGS05), the Key Project of Education Bureau of Hunan Province (23A0293), the Hunan Province Science and Technology Innovation Leading Talent Project (2021RC4034), the Key Project at Central Government Level: the ability establishment of sustainable use for valuable Chinese medicine resources (2060302)