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The same qualities that make these drugs effective individually, appetite suppression, metabolic shifts, cardiovascular stimulation, can compound in unpredictable ways when combined
According to the Wegovy Summary of Product Characteristics (SmPC), gastrointestinal disorders are very common during treatment
If heart rate increases are problematic at a particular dose level, discuss with your physician whether maintaining that dose longer before escalation, or potentially remaining at a lower maintenance dose, might be appropriate
Additionally, one prospective cohort study reported an inverse association between omega-3 fatty acid content of red blood cell membranes (an indicator of omega-3 fatty acid intake) and cognitive decline (172)
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