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Use the semaglutide dosage calculator on SeekPeptides for dosing specifics, but for calories, here is how to calculate your BMR: For women: BMR = (10 x weight in kg) + (6.25 x height in cm) - (5 x age) - 161 For men: BMR = (10 x weight in kg) + (6.25 x height in cm) - (5 x age) + 5 As a quick example, a 40-year-old woman who weighs 85 kg (187 lbs) and stands 165 cm (5 foot 5) tall would calculate: (10 x 85) + (6.25 x 165) - (5 x 40) - 161 = 850 + 1,031 - 200 - 161 = 1,520 calories
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But the really impressive numbers came from the SURPASS-5 trial, where tirzepatide reduced total cholesterol by 12.9%, LDL cholesterol by 15.5%, and triglycerides by a substantial 24.9%, while increasing HDL cholesterol by 0.9%
Previous approaches focused on short-term interventions with the expectation that patients would maintain losses independently