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After months on a GLP-1 medication, dietary habits often drift
In both mouse and human beta cells, the ability of GLP-1 to induce membrane depolarisation and initiate action potential firing depend on extracellular Na + and TRPM5 activity [23, 29, 30]
However, retatrutide's positive weight loss numbers were offset by its elevated discontinuation rate
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For example, oral tirzepatide candidates are already generating excitement in clinical trials
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