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Important cautions: Personal or family history of medullary thyroid cancer or Multiple Endocrine Neoplasia syndrome type 2: GLP-1s are contraindicated History of pancreatitis: Discuss risks carefully with your doctor Gallbladder issues: GLP-1s may increase gallstone risk Severe gastrointestinal disease: May worsen symptoms Pregnancy plans: Not recommended if youre trying to conceive Can GLP-1 mess with hormones? GLP-1s arent hormone therapy

Furthermore, when compared to patients not taking any of these other medications, the GLP-1 group displayed a recurrence risk of 14.5%, whereas the comparison group had a risk of 51.6%

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On the day Do not eat or drink for six hours before your procedure

6.2 Key endpoints in the PIONEER program (PIONEER 18) The primary endpoint in PIONEER 15 [39, 61, 62, 76, 77] and PIONEER 8 [82] was change from baseline in HbA 1c , while change from baseline in body weight at Week 26 was included as a secondary endpoint