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Patients should contact their GP or prescribing clinician if they experience : Severe or persistent diarrhoea lasting more than 48-72 hours despite conservative management Signs of dehydration , including reduced urine output, dark-coloured urine, dizziness, confusion, or persistent thirst Blood in stools or black, tarry stools (melaena) Severe abdominal pain , particularly if localised or accompanied by fever Unintentional weight loss beyond expected therapeutic effects Inability to maintain adequate oral fluid intake due to concurrent vomiting Urgent medical attention is required if patients develop symptoms suggestive of serious complications, including acute pancreatitis (severe upper abdominal pain radiating to the back, often with vomiting) or gallbladder disease (pain in the right upper abdomen, fever, or yellowing of the skin/eyes)
Up to 28 days refrigerated under proper conditions is the conservative guideline
Presented for research literature review only Herrera HO et al
Research suppliers provide cold chain packaging even in winter
Beyond its use in diabetes, Semaglutide is also employed for weight management, both in diabetic and non-diabetic individuals, due to its effectiveness in decreasing appetite and food intake
