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Sc profiling of endometrial organoids [1, 16, 62] revealed that in culture conditions without hormones, most cells are in a proliferative state ( TOP2A , PCNA ) and express ESR1 , indicating their existing responsiveness to E2 (Fig

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Results The case-control study comprised 294 ALS cases (60.2% men) with a mean age of 65.4 (SD 11.0) years and 504 controls (59.3% men) with a mean age of 66.3 (SD 10.3) years ( Table 1 )