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If there is clinical improvement and if a reticulocyte response is observed, the same amount may be given on alternate days for seven doses, then every 3 to 4 days for another 2 to 3 weeks

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Three RRM2 knockdown cell lines ( RRM2 -KD-323, RRM2 -KD-417, RRM2 -KD-506) were successfully constructed using the lentiviral LV2N (U6/Puro) system and transfected with MOI = 15 in TPC-1 and IHH4 cells

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