lip melanotic macule Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Oral Melanotic Macule: Symptoms and

Its primary action is to promote fat breakdown and reduce fat storage rather than alter appetite, nutrient absorption, or gastrointestinal function

The report described diffuse skin and gingival pigmentation that recurred after re-exposure

In combination with other agents, it can cause gene expression changes that single agents do not

Melanotan 1, is typically injected or administered as an implant, and binds to the melanocortin receptors 1, 3, 4, and 5 (MC1R, MC3R, MC4R, MC5R), with a strong effect on MC1R, leading to increased melanin production and tanning in test subjects [2, 3, 4, 5, 6]

doi: 10.1111/j.1432-1033.1997.00001.x 9 SchulzH