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In terms of ECM remodeling, collagen peptides activate the TGF-/Smad pathway, downregulate AP-1 and MMPs, and promote collagen synthesis, thereby counteracting UV-induced collagen degradation
In ALS, for instance, IGF-1 treatment lead to significant reductions in disease progression, increased muscle strength, improved respiratory functioning, and increased quality of life
The main drugs studied include immunoglobulins, glucocorticoids, monoclonal antibodies, anticoagulants, and antiplatelet agents [25]
Peptide drugs application in metabolic diseases and discovery strategies
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