facts about semaglutide and Weight Loss: What You Need to Know Generic Semaglutide in USA (2026):

For GLP-1 users specifically, I prioritize movements that protect the muscle groups most vulnerable to atrophy during rapid weight loss: Lower body: Squats ( meaning any form of knee bend), deadlifts, lunges (glutes, quads, and hamstrings are the largest muscle groups and the biggest contributors to metabolic rate) Upper back and lats: Rows, pulldowns (postural muscles that deteriorate quickly without stimulus) Chest and shoulders: Presses, overhead work, flyes (functional pushing strength) Core: Planks, Pallof presses, loaded carries (spinal stability, injury prevention) Safety Note: If nausea is severe during early titration, reduce training volume (fewer sets per exercise) rather than eliminating sessions

NHS access is subject to NICE eligibility criteria

And now, the other kind of weight loss medications that we talked about earlier - the unregulated and mostly ineffective ones

1 It works on the appetite centres in the brain to reduce hunger and quieten food noise, so you feel full sooner and eat less

Alexis Cutchins: You can see the angle of the SMA coming off the aorta during ultrasound if you have good technicians and good sonographers