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The MiniMed pumps work in closed loop only with the proprietary Guardian sensor
GLP-1 and exendin-4 show a similar nM affinity while glucagon, secretin, VIP and GLP-2 have at least a hundred times lower affinity for the GLP-1 receptor
The real-world data says most people do not manage ongoing treatment
Morning injection is most common because some users report mild energizing effects that could interfere with sleep if taken late in the day
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