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Ipamorelin treatment preserved bone mineral content and bone mechanical strength in glucocorticoid-treated rats compared to untreated controls

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In patients with T2D in a phase 2 clinical trial, retatrutide (0.5 to 12 mg) significantly reduced body weight and HbA1c levels compared to placebo and 1.5 mg dulaglutide

In a separate study [180] using a mouse model of amyloidosis and disrupted circadian clock function through an inducible whole-organism deletion of the core clock gene Bmal1 , these animals accumulated a higher hippocampal A plaque burden

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