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Still, these molecules also have multiple GSH-independent functions, which can potentially confound interpretations

768 N-acetylcysteine, a precursor to glutathione, plays a critical role in restoring glutathione balance, improving mitochondrial complex IV dysfunction, reducing cellular oxidative damage, and ameliorating neuromuscular dysfunctions in Leigh syndrome models

However, complete symptom resolution, particularly for neurological complications, may take several weeks to months depending on the severity and duration of deficiency before treatment

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