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A therapy that appeals to both male and female physiology, while staying independent of hormone levels, offers a level of versatility unmatched in many modern interventions

These frameworks consider factors such as hormone responses (including insulin, GLP-1, and leptin), individual differences in hunger and fullness control, and brain reward processing

YLC, BGO, SS, NMJ and HC contributed to the writing of the main manuscript text, and YLC prepared Figures 18 and Tables 1, 2