There are also three records of patient deaths following self-administered coffee enemas
Many people cant get enough B12 from food alone, so they take vitamin supplements or get B12 injections
For shortterm use (days to weeks), refrigeration at ~4C (39F) is generally acceptable
Org Lett 17(19):49024905 Villain M, Gaertner H, Botti P (2003) Native chemical ligation with aspartic and glutamic acids as C-terminal residues: scope and limitations
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