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doi: 10.3390/molecules24152678 19 TianJYongJDangHKaufmanDL
A composite example from my practice: Ive cared for a patient maximized on both a DMARD and a biologic, still flaring several times a month, exhausted, in pain
Recently, two mechanisms involved in the gut-brain axis have attracted increasing attention due to their role in the pathogenesis and progression of PD, namely, disruption of the composition of microorganisms living in the intestine (intestinal microbiome) and dysfunction of enteroendocrine cells, accompanied by impaired signaling through the GLP-1R [60]
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