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In the 1970s, however, research led by Dr
Chemoproteomics reveals baicalin activates hepatic CPT1 to ameliorate diet-induced obesity and hepatic steatosis
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Chromone-derived PDE10 inhibitors (Compound 68 ) show high metabolic stability (rat microsomal, t: 105 min) and strong selectivity, with C-6 substitution improving potency and stability but requiring careful control to avoid solubility loss (Yu et al., 2020)
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