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To diagnose hepatic steatosis, it is necessary to demonstrate fat accumulation in more than 5% of hepatocytes on histopathological examination, in the absence of significant alcohol consumption or other causes of liver injury or steatosis, or to detect more than 5.6% fat using proton magnetic resonance spectroscopy (H-MRS) [19]

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Custom-dose vials are designed to support more personalized dosing so patients and prescribers can fine-tune therapy (including slower titration when appropriate)

That includes signals tied to swelling, oxidative stress, and tissue breakdown

Researchers enrolled 201 adolescents with a BMI in the 95 th percentile or higher according to sex- and age-specific growth charts, or a BMI in the 85 th percentile or higher with at least one weight-related coexisting condition (62% girls