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J Am Geriatr Soc 69(8):23272334 Appari M, Channon KM, McNeill E (2017) Metabolic regulation of adipose tissue macrophage function in obesity and diabetes

PMID 25387

Increasing vitamin b12 can also promote better vision in older adults

Both peptides are derived from naturally occurring regulatory compounds and have been investigated in research models for their influence on neurotransmitter signaling, neurotrophic support, inflammatory pathways, and central nervous system function

Its formula is very nice: 0.2% retinal (which is a vitamin A derivative slightly less powerful than tretinoin but still quite effective) formulated in a very gentle emulsion to minimize irritation as much as possible