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Posttranslational stability of the heme biosynthetic enzyme ferrochelatase is dependent on iron availability and intact iron-sulfur cluster assembly machinery

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Similarly, Xie et al

In many chronic cases, the illness pattern is more accurately described as mycotoxin illness reflecting the systemic biological effects of retained mold toxins rather than surface-level mold allergy

This dysregulation is secondary to mutations in elements of the pathway that include the APC gene (adenomatous polyposis coli), -catenin, or other elements, which make the pathway to be constitutively active and has oncogenic consequences [118, 119]