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(1) Melanotan 1 comprises 13 amino acids, the same as -MSH, but differs by only two amino acids from the endogenous peptide hormone

Tulloch-Reid MK, Hanson RL, Sebring NG, Reynolds JC, Premkumar A, Genovese DJ, et al

88 STAT3 forms complexes with TOX, directly binding promoters of inhibitory receptors such as PD-1, TIM-3, and LAG-3, increasing chromatin accessibility and enforcing an exhausted phenotype

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