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Neither conclusion can be applied to humans at typical compounded doses (250 to 500 mcg subcutaneously) because: Rodent doses (10 mcg/kg intraperitoneally) do not translate linearly to human subcutaneous pharmacokinetics

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Sometimes that points back to: Chronic inflammation Poor mitochondrial support from stress, under recovery, or nutrient gaps Gut inflammation affecting absorption and immune balance Hormone shifts that change tissue resilience Blood sugar swings that raise baseline inflammation Not enough strength work, or too much repetitive work When you address those, you are not only chasing symptom relief