OA leads to pain, loss of motion, instability, and physical disability, thus impairing quality of life
Chen L, Na R, Gu M, Richardson A, Ran Q
While GSH donates electrons to counter free radicals and reactive oxygen species, it turns into GSSG, the inactive and oxidized form of glutathione
2013;1830(8):411729 Sands JM, Bichet DG, American College of Physicians, American Physiological Society
Depending on the intended site of action and nature of the gene-editing, the outcome of such treatment could differ drastically from the transient effects on both IgG and albumin achieved by first-generation FcRn antagonists