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For example, high-throughput, non-targeted profiling (UPLC-MS/MS) in five cultivars of A
De Fano et al.)
The phenomenon of ligand-directed signalling bias for GLP-1R has recently been described using the endpoints of cAMP production, pERK1/2 and intracellular Ca 2+
Although the adapted program is the optimal solution under current conditions, if the intracellular stress signal persists and the ER function cannot return to normal, the apoptotic program might be initiated (291)
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